Catherine C.L. Wong, PhD, Doctoral Supervisor
Director, Center for Precision Medicine Multi-Omics Research (CPMMR), Peking University Health Science Center
Tel: (86)010-82805975
Email: catherine_wong@bjmu.edu.cn
Director, Center for Precision Medicine Multi-Omics Research, Peking University Health Science Center
Principal Investigator, Center for Life Sciences, Peking Unversity & Tsinghua University
Associate Professor with Tenure, School of Basic Medical Sciences, Peking University Health Science Center
Principal Investigator, State Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center
Honorary Professorship, Faculty of Biology, Medicine and Health, The University of Manchester
The Introduction of Outstanding Talents for Technology, Chinese Academy of Sciences
Committee Member of Center for Transformation of Scientific and Technological Achievements, Peking University Health Science Center
Committee Member of Protein Society, The Chinese Society of Biochemistry and Molecular Biology
Chairman Member of Committee of Experimental Medicine (Mass Spectrometry), National Association of Health Industry and Enterprise Management
Committee Member of China Human Proteome Organisation
Education & Positions
B.S. in Chemistry/Sociology, Chinese University of Hong Kong, China, 1990-1994.
M.S. in Chemistry, The University of Hong Kong, China, 1996-1998.
Ph.D. in Chemistry, The University of Hong Kong, China, 2000-2003.
Research Associate, Chi-ming Che Lab, Dept. of Chemistry, The University of Hong Kong, China, 2004–2005.
Postdoctoral Fellow, John R Yates III Lab, The Scripps Research Institute (TSRI), La Jolla, CA, USA, 2005–2007.
Senior Staff Scientist/Lab Manager, John R Yates III Lab, The Scripps Research Institute (TSRI), La Jolla, CA, USA, 2007-2013.
Principal Investigator/Professor, Head of Mass Spectrometry Division, National Center for Protein Science, Shanghai, SIBCB, CAS, 2013-2017.
Director of Center for Precision Medicine Multi-Omics Research, Principal Investigator of Center for Life Sciences, 2017-Present.
Research Interests
1. Development of cutting-edge mass spectrometry technologies, including single cell proteomics, new methods on glycoproteins identifications and quantifications based on Trapped Ion Mobility-TOF MS and new protein database search algorithms development.
2. Biomarker exploration based on disease problems and clinical cohorts using multi-omics technologies, combined with biotechnology, chemical biology and other interdisciplinary technologies for functional verification and mechanism analysis.
Selected Publications
1. Li, Z. Y., Huang, M., Wang, X. K., Zhu, Y., Li, J. S., Wong, C. C. L.,* Fang, Q*., Nanoliter-Scale Oil-Air-Droplet Chip-Based Single Cell Proteomic Analysis. Anal Chem, 2018, 90(8):5430-5438.
2. Tao, Z., Meng, X., Han, Y. Q.., Xue, M. M., Wu, S., Wu, P., Yuan, Y., Qiang, Z., Zhang, T.-J.* and Wong, C. C. L.,* Therapeutic Mechanism Studies of ShuFengJieDu Capsule on an Acute Lung Injury Animal Model Using Quantitative Proteomics Technology, Journal of proteome research, 2017, 16(11):4009-4019.
3. Liu, M.-Q., Zeng, W.-F., Fang, P., Cao, W.-Q., Liu, C., Yan, G.-Q., Zhang, Y., Peng, C., Wu, J.-Q., Zhang, X.-J., Tu, H.-J., Chi, H., Sun, R.-X., Cao, Y., Dong, M.-Q., Jiang, B.-Y., Huang, J.-M., Shen, H.-L., Wong, C. C. L.,* He, S.-M.* and Yang, P.-Y.* , pGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification, Nature Communications, 2017, 8(1):438
4. Hao, Q., Jiao, S., Shi, Z., Li, C., Meng, X., Wang, W., Song, X., Jiang, Z., Zhao, Y., Wong, C. C. L.,* and Zhou, Z.,* A non-canonical role of the p97 complex in RIG-I antiviral signaling, EMBO Journal, 2015, 34(23):2903-2920
5. Yan, C., Huang, J., Wan, R., Huang, M., Wong, C. C. L., and Shi, Y., Structure of a yeast Spliceosome at 3.6-angstrom resolution, Science, 2015, 349(6253):1182-1191
6. Keck, J. M., Jones, M. H., Wong, C. C. L., Binkley, J., Chen, D., Holinger, E. P., Niepel, M., Rout, M., Vogel, J., Sidow, A., Yates 3rd, J. R., and Winey, M., A Cell Cycle Phosphoproteome of the Yeast Centrosome, Science, 2011, 332(6037):1557-1561
7. Xu, T#., Wong, C. C. L.#(co-first Author), Kashina, A., and Yates 3rd, J. R., Identification of N-terminally Arginylated Proteins and Peptides by Mass Spectrometry, Nature Protocol, 2009, 4(3):325-332
