Yang Chen, Tenure-track Assistant Professor
Contact information:
Mailing address:
1/F, Building 12,
Peking University Medical Industry Park,
Changping District,
Beijing 102200
China
Phone: 86 (10) 13811813772
Email: chenyang1816185048@bjmu.edu.cn
Education:
2008~2012 Ph.D., Basic medical science, Peking University, Beijing, P.R. China/
Cellular biology and metabolism program, National Institute of Health,
Major: Cell biology/Molecular biology and biochemistry
Mentor: Dr. Matthias Machner/ Dr. Yang Ke
2004~2008 B.S, Basic medical science, Peking University, Beijing, P.R. China
Major: Basic medical science
Research Experience:
Aug. 2018- present Tenure track assistant professor, Center for Precision Medicine Multi-
Omics Research, Peking University Health Science Center, Peking
University,
Jan. 2017~July. 2018 Associate professor, School of life science, Tsinghua university
(Research Track)
Sep. 2014~Dec. 2016 Assistant professor, School of life science, Tsinghua university
(Research Track)
Sep. 2012~2014 Postdoctoral fellow, School of life science, Tsinghua university
Mentor: Dr. Yu, Li
BIBLIOGRAPHY
Original publications: (* represents first author)
1.Xiaoxin Zhao*, Yaxin Lei, Jiajia Zheng, Junya Peng, Ying Li, Li Yu, and Yang Chen (2019). Identification of markers for migrasome detection. Cell Discovery, 2019 May 21;5:27. (co-corresponding author)
2.Mi N*, Chen Y*, Wang S, Chen M, Zhao M, Yang G, Ma M, Su Q, Luo S, Shi J, Xu J, Guo Q, Gao N, Sun Y, Chen Z, Yu L. CapZ regulates autophagosomal membrane shaping by promoting actin assembly inside the isolation membrane. Nature Cell Biology. 2015 Jan; 25(1): 24-38 (co-first author)
3.Du W*, Su QP*, Chen Y*, Zhu Y, Jiang D, Rong Y, Zhang S, Zhang Y, Ren H, Zhang C, Wang X, Gao N, Wang Y, Sun L, Sun Y, Yu L. Kinesin 1 Drives Autolysosome Tubulation. Developmental Cell. 2016 May 23; 37(4): 326-36 (co-first author)
4.Neunuebel MR*, Chen Y*, Gaspar AH, Backlund PS Jr, Yergey A, Machner MP. De-AMPylation of the small GTPase Rab1 by the pathogen Legionella pneumophila. Science. 2011 Jul 22; 333(6041): 453-6 (co-first author)
5.Chen Y*, Tascón I*, Neunuebel MR, Pallara C, Brady J, Kinch LN, Fernández-Recio J, Rojas AL, Machner MP, Hierro A. Structural basis for Rab1 de-AMPylation by the Legionella pneumophila effector SidD. PLOS Pathogen. 2013 May 16; (co-first author)
6.Chen Y*, Machner MP. Targeting of the small GTPase Rab6A' by the Legionella pneumophila effector LidA. Infection and Immunity. 2013 Jun 881(6): 2226-35
Reviews:
1.Chen Y*, Su Q*, Sun YJ, Yu L. Visualizing autophagic lysosome reformation in cells using in vitro reconstitution systems. Current Protocols in Cell Biology, 2018 Mar;78(1):11.24.1-11.24.15.
2.Chen Y, Li Y, Ma L, Yu L. Detection of migrasomes. Cell Migration: Methods and Protocols, Methods in Molecular Biology, vol. 1749, 2018
3.Chen Y, Li Y. Development of research into autophagic lysosome reformation. Molecules and Cells. 2018 Jan 31;41(1):45-49.
4.Yu L, Chen Y, Tooze SA. Autophagy pathway: cellular and molecular mechanisms. Autophagy. 2017 Sep 21:1-9.
5.Chen Y*, Yu L, Recent progress in autophagic lysosome reformation. Traffic. 2017 Jun; 18(6): 358-361.
6.Chen Y*, Yu L, Research progress of membranous organelles and their subcellular structures in China. Chinese Science Bulletin 2017 May 12;
7.Chen Y*, Yu L, Scissors for autolysosome tubules. EMBO J. 2015 Sep 2; 34(17): 2217-8.
8.Chen Y*, Yu L. Autophagic lysosome reformation. Exp Cell Res. 2013 Jan 15;319(2):142-6
9.Machner MP*, Chen Y, Catch and release: Rab1 exploitation by Legionella pneumophila. Cell Logist. 2011 Jul 1; 1(4): 133-138.
